CHEMISTRY QUESTION-WEBSITE EDIT

I need you to build an academic-style website for my university assignment. I will provide you with:

1. My written report (PharmaNova document)
2. My presentation slides ()
3. A website link/template for editing ()

The website must look professional, clean, and scientific (like a pharmaceutical company website), not casual or blog-style.

STRUCTURE (VERY IMPORTANT must follow this exactly):

The website should have approximately 8 sections/pages:

1. Home Page

• Company name: PharmaNova
• Tagline (e.g. Innovating Targeted Therapies for Intestinal Disease)
• Brief overview of our drug and purpose
• Clean hero section with scientific feel

1. About the Disease & Target

• Explain diarrhoea (global burden)
• Explain P2Y14 receptor (GPCR, role in inflammation and necroptosis)
• Why this target matters

1. Drug Discovery (Hit Identification)

• Explain how Hit 1 and Hit 2 were discovered
  (HTS + virtual screening)
• Brief explanation of assays (radioligand, FLIPR)
• Show structures (if possible)

1. Lead Optimisation

• Show how hits were improved
• Explain Compound 66 66-M
• Explain Compound 8 8-MM
• Focus on WHY changes were made (LogP, metabolism, etc.)

1. Final Lead Compound

• Highlight Compound 66-M
• Why it was selected (potency, PK, permeability)
• Comparison vs other compound

1. Tablet Formulation (DETAILED SECTION VERY IMPORTANT)

• Why tablet formulation was chosen
• Full breakdown of excipients:
  • Binder
  • Filler
  • Disintegrant
  • Lubricant
  • Coating
• Explain role of each clearly
• Must look scientific and detailed

1. Challenges & Alternative Formulation

• Challenges (solubility, permeability, stability, etc.)
• ONE alternative formulation (e.g. capsule or liquid)
• Pros and cons vs tablet

1. Sustainability & Future Steps

• Social responsibility (global diarrhoea burden)
• Access to medicine
• Cost considerations
• Environmental/sustainable manufacturing
• Next steps (preclinical clinical trials)

DESIGN REQUIREMENTS (VERY IMPORTANT):

• The design must look visually attractive and professional (high distinction level)
• Clean layout with clear sections (not blocks of text)
• Use a modern pharmaceutical style (white + blue/green color theme)
• Use headings, spacing, and visual hierarchy properly
• Include icons, cards, or sections to break content
• Make it look like a real biotech/pharma company website
• Ensure it is easy to read and visually engaging

DIAGRAMS & FIGURES:

• Review the diagrams and figures in the files I provide
• Only include diagrams that are clear, labelled, and professional
• If any diagrams are low quality or unclear, improve or redesign them
• Chemical structures must be clearly visible and labelled (Figure 1, Figure 2, etc.)
• Use visuals to support explanation, not just decoration

CONTENT RULES:

• DO NOT change scientific meaning
• Improve readability but keep academic tone
• Break long text into sections
• Highlight key points

EXTRA:

• Include placeholders for chemical structures if needed
• Make sure navigation is smooth (menu at top)
• Each section should feel like its own page

DEADLINE:
I need this completed by the 26th.

I will provide all materials your job is to structure, design, and present it professionally.

Criteria of grading:

BRIEF OVERVIEW of new medicine – There is a clear concise and overview, no flaws in logic, demonstrates insight

BRIEF SUMMARY of disease and target – There is a clear concise and overview, no flaws in logic, demonstrates insight

BRIEF SUMMARY of hit discovery and optimisation to give lead compound – There is a clear concise and overview, no flaws in logic, demonstrates insight

DETAILED DESCRIPTION of tablet formulation of your lead compound – There is a clear and detailed description, with STRONG evidence of high-level understanding

BRIEF DESCRIPTION of one other possible formulation that could be suitable for your lead compound – There is a clear and concise description

DETAILED DESCRIPTION of sustainability and social responsibility issues that relate to your disease/target/drug, and how you could address them – There is a clear and detailed description, with STRONG evidence of high-level understanding

BRIEF DESCRIPTION of the next steps for your formulated medicine – There is a clear and concise descrption

Website structure – Website is straightforward to navigate, intellectually engaging